Side effects of pulsatile GnRH therapy for induction of ovulation

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Successful use of pulsatile gonadotropin-releasing hormone (GnRH) for ovulation induction and pregnancy in a patient with GnRH receptor mutations.

GnRH receptor mutations have recently been identified in a small number of familial cases of nonanosmic hypogonadotropic hypogonadism. In the present report we studied a kindred in which two sisters with primary amenorrhea were affected with GnRH deficiency due to a compound heterozygote mutation (Gln(106)Arg, Arg(262)Gln) and performed extensive phenotyping studies. Baseline patterns of gonado...

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ژورنال

عنوان ژورنال: Expert Review of Endocrinology & Metabolism

سال: 2008

ISSN: 1744-6651,1744-8417

DOI: 10.1586/17446651.3.5.535